Table 1.
Impacted untargeted pathways associated with field assessment based on gamma P < 0.10
| Pathway | Total in pathway | Total detected | Significant hits | Gamma P |
|---|---|---|---|---|
| Glycerophospholipid metabolisma | 156 | 24 | 12 | >0.01 |
| Fatty acid activation | 74 | 23 | 9 | >0.01 |
| Phosphatidylinositol phosphate metabolism | 59 | 5 | 3 | 0.01 |
| Purine metabolisma | 80 | 13 | 5 | 0.01 |
| Ubiquinone biosynthesis | 10 | 2 | 2 | 0.01 |
| Androgen and estrogen biosynthesis and metabolism | 95 | 10 | 4 | 0.01 |
| Saturated fatty acids beta-oxidation | 36 | 7 | 3 | 0.02 |
| Methionine and cysteine metabolism | 94 | 7 | 3 | 0.02 |
| Prostaglandin formation from di-homo gamma-linoleic acid | 11 | 3 | 2 | 0.02 |
| Glycosphingolipid metabolism | 67 | 20 | 6 | 0.02 |
| Fatty acid oxidation | 35 | 8 | 3 | 0.02 |
| Butanoate metabolism | 34 | 8 | 3 | 0.02 |
| Glycine, serine, alanine and threonine metabolism | 88 | 13 | 4 | 0.03 |
| Linoleate metabolism | 46 | 18 | 5 | 0.03 |
| Caffeine metabolism | 1 | 5 | 2 | 0.04 |
| Urea cycle/amino group metabolism | 85 | 21 | 5 | 0.05 |
| Omega-3 fatty acid metabolism | 39 | 6 | 2 | 0.05 |
| Phytanic acid peroxisomal oxidation | 34 | 6 | 2 | 0.05 |
| Glycolysis and gluconeogenesis | 49 | 7 | 2 | 0.07 |
| Di-unsaturated fatty acid beta-oxidation | 26 | 7 | 2 | 0.07 |
| Carnitine shuttle | 72 | 33 | 7 | 0.07 |
| Hexose phosphorylation | 20 | 8 | 2 | 0.08 |
The gamma P cutoff of 0.1 was used to ensure weakly related pathways are retained for further investigation.
a
Also significant in target pathway analysis.