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. Author manuscript; available in PMC: 2024 Jul 13.
Published in final edited form as: Chem. 2023 May 11;9(7):1658–1701. doi: 10.1016/j.chempr.2023.04.010

Figure 8. Iron deoxygenase-catalyzed intermolecular aziridination by Goldberg.

Figure 8.

(A) Schematic of iron-bound metalloprotein.

(B) Image of most active enzyme with 5 mutations highlighted in blue.

(C) Overall transformation with optimized conditions and best reported result. Reprinted (adapted) with permission from Goldberg et al.39 Copyright 2019 American Chemical Society. PDBID: 6CBA.