TABLE 1.
Initial comparison of the LCx M. tuberculosis Assay with culture for the detection of M. tuberculosis in 526 nonrespiratory specimens
| Specimen type (no.) | No. of specimens with result
|
% Sensitivity | % Specificity | % PPV | % NPV | |||
|---|---|---|---|---|---|---|---|---|
| Culture positive
|
Culture negative
|
|||||||
| LCx positive | LCx negative | LCx positive | LCx negative | |||||
| Smear positive (61) | 33 | 0 | 4a | 24b | 100 | 85.7 | 89.1 | 100 |
| Smear negative (465) | 68 | 29 | 1c | 367d | 70.1 | 99.7 | 98.5 | 92.6 |
| All (526) | 101 | 29 | 5 | 391 | 77.7 | 98.7 | 95.2 | 93.1 |
a
From four patients with active TB treated with anti-TB drugs for 1 to 7 months.
b
Twenty-four specimens with culture positive for NTM.
c
From one patient with active cervical tuberculous lymphadenitis.
d
Fourteen specimens with culture positive for NTM.