Table 2.

Significant gut microbes associated with breast cancer based on the FinnGen database.

Gut bacteria	Outcome	NSNP	Method	OR	95%CI	Value of p	FDR
Genus_Ruminococcus2	Her2+ Breast cancer	13	Inverse variance weighted	0.77	0.67–0.89	4.91E-04	0.04
Genus_Ruminococcus2	Her2+ Breast cancer	13	Weighted median	0.73	0.60–0.89	1.82E-03	0.22
Genus_Ruminococcus2	Her2+ Breast cancer	13	MR Egger	0.70	0.48–1.01	0.06	0.99
Genus_Erysipelatoclostridium	Her2+ Breast cancer	14	Inverse variance weighted	1.25	1.10–1.41	6.58E-04	0.04
Genus_Erysipelatoclostridium	Her2+ Breast cancer	14	Weighted median	1.28	1.07–1.54	6.20E-03	0.37
Genus_Erysipelatoclostridium	Her2+ Breast cancer	14	MR Egger	1.12	0.68–1.83	0.67	0.91

MR, Mendelian randomization; NSNP, number of single nucleotide polymorphisms; OR, odds ratio; CI, confidence interval; FDR, false discovery rate.