Table 2.
Crude and adjusted hazard ratios of gout for cardiovascular disease.
| Dependent variable | IR per 1000 person-year |
IRD per 1000 person-years (95% CI) |
Hazard ratios for cancers (95% confidence interval) | ||||
|---|---|---|---|---|---|---|---|
| Gout (n=3070) |
Control (n=12,280) |
Crude† | p-value | Adjusted†‡ | p-value | ||
| Stroke (n = 3099) | 9.84 | 8.41 | 1.43 (0.79–2.08) | 1.17 (1.09–1.26) | <0.001* | 1.11 (1.04–1.19) | 0.003* |
| Ischemic heart disease (n = 2863) | 9.77 | 7.15 | 2.62 (2.00–3.24) | 1.36 (1.27–1.47) | <0.001* | 1.28 (1.19–1.37) | <0.001* |
| Heart failure (n = 688) | 2.47 | 1.46 | 1.01 (0.72–1.30) | 1.69 (1.45–1.97) | <0.001* | 1.64 (1.41–1.91) | <0.001* |
IR, incidence rate; IRD, incidence rate difference; CI, confidence interval.
*Stratified Cox proportional hazard regression model, Significance at p < 0.05.
†Models were stratified by age, sex, income, and region of residence.
‡The Model was adjusted for obesity, smoking, alcohol consumption, systolic blood pressure, diastolic blood pressure, fasting blood glucose, total cholesterol, hemoglobin, and CCI scores.