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. 2023 Aug 23;14:1215236. doi: 10.3389/fmicb.2023.1215236

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Copyright © 2023 Katagiri, Ohsugi, Shiba, Yoshimi, Nakagawa, Nagasawa, Uchida, Liu, Lin, Tsukahara, Iwata and Tohara.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Metagenome prediction between RTF and HBTF groups (n = 6 and 5, respectively). (A) Upregulated genes (p < 0.01) predicted Kyoto Encyclopedia of Genes and Genome (KEGG) pathways in the oral microbiome of the HBTF group (green) in the microbial metabolism map. No predicted KEGG pathway was upregulated in the RTF group. (B) Predicted KEGG pathways of the upregulated genes (p < 0.01) in the gut microbiome of the RTF (red) or HBTF groups (yellow) in the microbial metabolism map. RTF, ready-made tube feeding; HBTF, homemade blenderized tube feeding.