Table 2:
Validation estimates by province and quarter: inpatient cohort
| Measure | Estimate, % (95% CI) | |||
|---|---|---|---|---|
| Q1 April 2020–June 2020 |
Q2 July 2020–September 2020 |
Q3 October 2020–December 2020 |
Q4 January 2021–March 2021 |
|
| British Columbia | ||||
| Sensitivity | 88.4 (84.8–92.1) | 56.1 (49.8–62.4) | 52.0 (49.7–54.3) | 53.5 (51.6–55.4) |
| Specificity | 97.5 (97.3–97.7) | 97.7 (97.5–97.8) | 97.5 (97.4–97.7) | 98.3 (98.2–98.5) |
| PPV | 30.0 (26.9–33.0) | 17.8 (15.1–20.6) | 46.9 (44.8–49.1) | 58.9 (57.0–60.9) |
| NPV | 99.9 (99.8–99.9) | 99.6 (99.5–99.7) | 98.0 (97.8–98.1) | 97.9 (97.8–98.1) |
| Youden Index | 0.86 | 0.54 | 0.49 | 0.52 |
| Manitoba | ||||
| Sensitivity | 88.9 (77.0–100.0) | 75.4 (67.5–83.3) | 59.1 (56.4–61.8) | 48.2 (44.1–52.3) |
| Specificity | 99.6 (99.4–99.7) | 99.3 (99.1–99.5) | 95.3 (94.9–95.6) | 98.5 (98.3–98.7) |
| PPV | 46.2 (32.6–59.7) | 60.6 (52.5–68.6) | 55.4 (52.7–58.0) | 53.6 (49.4–57.9) |
| NPV | 99.9 (99.9–100.0) | 99.6 (99.5–99.8) | 95.9 (95.5–96.2) | 98.1 (97.9–98.3) |
| Youden Index | 0.88 | 0.75 | 0.54 | 0.47 |
| Ontario | ||||
| Sensitivity | 86.0 (84.8–87.1) | 73.0 (70.2–75.8) | 62.3 (61.0–63.6) | 71.0 (70.1–72.0) |
| Specificity | 98.8 (98.8–98.9) | 99.8 (99.8–99.8) | 98.8 (98.8–98.9) | 98.0 (97.9–98.1) |
| PPV | 75.0 (73.6–76.4) | 73.6 (70.9–76.4) | 68.3 (66.9–69.6) | 68.9 (67.9–69.8) |
| NPV | 99.4 (99.4–99.5) | 99.8 (99.7–99.8) | 98.5 (98.4–98.5) | 98.2 (98.1–98.3) |
| Youden Index | 0.85 | 0.73 | 0.61 | 0.69 |
Note: CI = confidence interval, NPV = negative predictive value, PPV = positive predictive value, Q = quarter.