Table 3.

Mixed model results from the start of the day shift and end of the night shift sampling time points that coincide in clock time (06:00 h).

Metabolite	Class	Minimally adjusteda				Fully adjustedb
		GMR	95%CI		P value	GMR	95%CI		P value
alanine	amino acid	0.98	0.54	1.79	0.95	0.70	0.25	1.98	0.51
arginine	amino acid	1.71	1.15	2.54	0.01	2.30	1.25	4.23	0.01
aspartate	amino acid	0.99	0.93	1.06	0.79	0.97	0.88	1.07	0.56
citrulline	amino acid	2.08	1.30	3.33	0.00	1.94	0.92	4.08	0.08
glutamine	amino acid	1.64	0.85	3.18	0.14	2.22	1.53	3.24	0.00
phenylalanine	amino acid	1.26	0.64	2.47	0.50	1.66	0.63	4.37	0.30
kynurenine	biogenic amine	1.69	0.75	3.83	0.21	3.22	1.05	9.87	0.04
carnitine	acylcarnitines	1.16	0.57	2.39	0.68	1.06	0.38	2.95	0.91
tetradecenoylcarnitine	acylcarnitines	0.60	0.34	1.08	0.09	0.84	0.33	2.12	0.71
lysoPCaC18:2	glycerophospholipids	1.70	1.11	2.59	0.02	1.86	1.11	3.11	0.02
lysoPCaC20:3	glycerophospholipids	1.77	1.06	2.94	0.03	2.48	1.05	5.83	0.04
lysoPCaC26:0	glycerophospholipids	1.03	0.59	1.80	0.92	0.65	0.28	1.53	0.33
lysoPCaC28:0	glycerophospholipids	1.90	1.15	3.14	0.01	0.74	0.30	1.80	0.51
PCaaC32:0	glycerophospholipids	1.45	0.88	2.40	0.15	0.96	0.43	2.13	0.91
PCaaC34:2	glycerophospholipids	1.54	0.54	4.44	0.42	2.27	1.16	4.44	0.02
PCaaC 40:3	glycerophospholipids	0.80	0.59	1.08	0.15	0.93	0.48	1.81	0.82
PCaeC30:0	glycerophospholipids	2.18	1.33	3.55	0.00	1.06	0.34	3.26	0.92
PCaeC36:4	glycerophospholipids	1.00	0.64	1.57	0.99	2.04	1.00	4.15	0.05
PCaeC38:1	glycerophospholipids	1.19	0.77	1.83	0.43	1.38	0.67	2.86	0.38
PCaeC38:5	glycerophospholipids	1.33	0.92	1.92	0.12	1.66	1.02	2.68	0.04

^aAdjusted for daylight,

^badjusted for daylight, aMT6s level, step count in last 24 hours, smoking in last 24 hours and sleep duration during last 24 hours