Fig. 2.

MD simulations reveal slowed dynamics of sterols in the presence of natamycin.

Sterol tilt angle distributions for POPC/cholesterol (A) and POPC/ ergosterol membranes (B). Autocorrelation functions of the sterol tilt angles are plotted as a function of the lag time, ACF(t). The individually colored lines show data for pure POPC/cholesterol (C) or POPC/ergosterol membranes (D). The bilayers in all panels contained either no natamycin (blue lines), natamycin as monomers (orange lines), antiparallel dimers (green lines), or parallel dimers (red lines). See main text for further explanations.