Table 3.
Summary of Recommendations on the Use of the ELF and VCTE for Risk-Stratification in Patients With NAFLD.
| Recommendations | Guidelines |
|---|---|
| ELF | |
| Cutoff of <7.7 and >9.8 | AACE. (1) |
| Cutoff of <10.35 | Egyptian guidelines. (1) |
| Cutoff of <0.3576 (equivalent of 10.17 on the Siemens scale) | KASL. (1) |
| Cutoff of <10.51 | NICE-UK. (1) |
| ELF is recommended but did not specify cutoffs | APASL, EASL, BSG, AFEF. (4) |
| ELF is useful but limited by availability, and thus not recommended | BASL, AASLD, DGVS. (3) |
| ELF was not mentioned | AISF, AGA, ALEH, Catalan guidelines, CSG, SBH, JSG, DGVS, INASL (9) |
| VCTE | |
| Cutoff of <8 and >12 | AACE, AGA, DGVS. (3) |
| Cutoff of <8 | IASF, ALEH. (2) |
| Cutoff of <7.9 (M-probe), <7.2 (XL-probe) | BASL. (1) |
| Cutoff of <9.9 | AASLD. (1) |
| Cutoff of <10 and >15 | APASL. (1) |
| Cutoff of <8 and >18 | Catalan guidelines. (1) |
| Cutoff of <7.9 and >9.6 | AFEF. (1) |
| VCTE is recommended, but there is no acceptable threshold for diagnosis and the optimum pathway has not been determined | CSGS, EASL, BSG, INASL. (4) |
| VCTE is recommended but did not specify cutoff | Egyptian guidelines, KASL, JSG, AAEH. (4) |
| VCTE was not mentioned | NICE-UK. (1) |
Abbreviations: AACE, American Association of Clinical Endocrinology; AAEH, Asociación Española para el Estudio del Hígado; AASLD, American Association for the Study of Liver Diseases; AFEF, French Association for the Study of the Liver; AGA, American Gastroenterology Association; AISF, Italian Association for the Study of the Liver; ALEH, Latin American Association for the study of the liver; APASL, The Asian Pacific Association for the Study of the Liver; BASL, Belgian Association for the Study of the Liver; BSG, British Society of Gastroenterology; CSG, Chinese Society of Gastroenterology; DGVS, German Society of Gastroenterology, Digestive and Metabolic Diseases; EASL, European Association for the Study of the Liver; ELF, enhanced liver fibrosis score; INASL, India National Association for the Study of the Liver; JSG, Japanese Society of Gastroenterology; KASL, The Korean Association for the Study of the Liver; NAFLD, Non Alcoholic Fatty Liver Disease; NICE, National Institute for Health and Care Excellence; VCTE, vibration-controlled transient elastography.