Table 2.
Histological Parameters Distribution According to Autoantibodies.
| Autoantibodies negative (n = 402) |
Only ANA positive (n = 43) | Only ASMA positive (n = 99) | ANA and ASMA positive (n = 99) | P value | |
|---|---|---|---|---|---|
| Steatosis | 0.374 | ||||
| Absent | 20 (5.2%) | 10 (7.1%) | 8 (8.2%) | 1 (2.6%) | |
| Mild | 192 (49.6%) | 71 (50.4%) | 41 (41.8%) | 16 (42.1%) | |
| Moderate | 133 (34.4%) | 50 (35.5%) | 36 (36.7%) | 13 (34.2%) | |
| Severe | 42 (10.9%) | 10 (7.1%) | 13 (13.3%) | 8 (21.1%) | |
| Activity | 0.099 | ||||
| Minimal | 377 (93.8%) | 128 (89.5%) | 93 (93.9%) | 34 (87.2%) | |
| Mild | 22 (5.5%) | 14 (9.8%) | 5 (5.1%) | 3 (7.7%) | |
| Moderate | 3 (0.7%) | 1 (0.7%) | 1 (1%) | 2 (5.1%) | |
| Ballooning | 0.788 | ||||
| Absent | 24 (6%) | 8 (5.6%) | 8 (8.1%) | 4 (10.3%) | |
| Few | 283 (70.4%) | 102 (71.3%) | 64 (64.6%) | 24 (61.5%) | |
| Many | 95 (23.6%) | 33 (23.1%) | 27 (27.3%) | 11 (28.2%) | |
| Fibrosis | 0.215 | ||||
| Portal, periportal (F1–F2) | 183 (85.1%) | 67 (90.5%) | 53 (94.6%) | 18 (85.7%) | |
| Advanced fibrosis (F3–F4) | 32 (14.9%) | 7 (9.5%) | 3 (5.4%) | 3 (14.3%) |
ANA, antinuclear antibody; ASMA, anti-smooth muscle antibodies.