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. Author manuscript; available in PMC: 2024 Apr 25.
Published in final edited form as: Mol Psychiatry. 2023 Mar 7;28(12):5262–5271. doi: 10.1038/s41380-023-02014-1

Fig. 3. Genes at OOA-specific risk loci for mood disorders interact with neuropsychiatry-related gene networks.

Fig. 3

A Putative OOA risk genes (820 genes; MAGMA, P < 0.01) had an elevated rate of protein-protein interactions with gene sets derived from GWAS, rare variant studies, differential gene expression, and network analyses of psychiatric disorders. B Protein-protein interactions among the top 250 genes at OOA risk loci prioritized by their centrality in a gene network centered on known neuropsychiatry-related genes and strength of their statistical association with mood disorders in the OOA. Larger node size corresponds to more significant MAGMA p values.