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. Author manuscript; available in PMC: 2024 Apr 25.
Published in final edited form as: Mol Psychiatry. 2023 Mar 7;28(12):5262–5271. doi: 10.1038/s41380-023-02014-1

Table 1.

Summary of risk loci.

Locus
 Cytoband 3q28/29 5q13 7q22 16q21
 Bounds (r2 > 0.6) chr3:190970484-193299693 chr5:74704443-76506247 chr7:99213680-111440525 chr16:62294564-62303850
 Width (r2 > 0.6) 2.7 Mb 6.1 Mb 10.5 Mb 9.2 kb
 N SNPs (r2 > 0.6) 15 6 71 7
 Bounds (D’ > 0.9) chr3:187812688-195437973 chr5:71732447-80465342 chr7:100470502-107647081 chr16:58087965-66459275
 Width (D’ > 0.9) 7.6 Mb 8.7 Mb 7.2 Mb 8.4 Mb
 N SNPs (D’ > 0.9) 207 538 1584 1405
Lead SNP
 SNP chr3:191857829:C:A chr5:76339511:G:A chr7:103511937:C:T chr16:62294564:T:C
 rsID rs192622352 rs569742752 rs117752843 rs7185072
 Amish MAF 0.004 0.004 0.019 0.311
 Beta 0.66 0.74 0.28 0.08
 Odds ratio 26.6 45.5 5.1 2.0
 P 3.4e-8 5.4e-10 1.3e-8 2.7e-8
 Aff/Unaff 7/2 8/2 27/34 133/64
 Relative risk 6.4 (4.4–9.4) 6.7 (4.8–9.3) 4.0 (2.9–5.4) 2.1 (1.6–2.8)