TABLE 8.

An overview of functional annotation analysis for annotated genes associated with filtered DMCs in experiments B, C, D and E. No significant terms were enriched for experiment A. The p-value was benjamini corrected to correct for multiple testing.

		Database	Enriched term	Adjusted p-value
Exp B	Hypo	INTERPRO	IPR000233:Cadherin, cytoplasmic domain	1.38E-04
		INTERPRO	IPR027397:Catenin binding domain	0.0021
		INTERPRO	IPR003598:Immunoglobulin subtype 2	0.0144
		INTERPRO	IPR000863:Sulfotransferase domain	0.0151
		INTERPRO	IPR003591:Leucine-rich repeat, typical subtype	0.0151
	Hyper	INTERPRO	IPR000233:Cadherin, cytoplasmic domain	4.14E-05
		INTERPRO	IPR027397:Catenin binding domain	5.62E-05
		INTERPRO	IPR014868:Cadherin prodomain	0.0017
		GOTERM_BP	GO:0071346∼cellular response to interferon-ϒ	0.0027
		INTERPRO	IPR020894:Cadherin conserved site	0.0083
Exp C	Hypo	GOTERM_MF	GO:0004689∼phosphorylase kinase activity	3.11E-12
		KEGG_PATHWAY	sasa04626: Plant-pathogen interaction	3.07E-07
		KEGG_PATHWAY	sasa04016: MAPK signaling pathway - plant	5.17E-07
		KEGG_PATHWAY	sasa04070: Phosphatidylinositol signaling system	3.74E-05
		KEGG_PATHWAY	sasa05133: Pertussis	7.61E-05
Exp D	Hypo	INTERPRO	IPR003598:Immunoglobulin subtype 2	0.0488
		INTERPRO	IPR003591:Leucine-rich repeat, typical subtype	0.0488
	Hyper	GOTERM_MF	GO:0004689∼phosphorylase kinase activity	2.00E-08
		UniProt_BP	KW-0524∼Neurogenesis	1.91E-04
		KEGG_PATHWAY	sasa04016:MAPK signaling pathway - plant	2.27E-04
		KEGG_PATHWAY	sasa04626:Plant-pathogen interaction	3.94E-04
		KEGG_PATHWAY	sasa04745:Phototransduction - fly	0.0016
Exp E	Hypo	INTERPRO	IPR020479:Homeodomain, metazoa	0.0036
		INTERPRO	IPR017970:Homeobox, conserved site	0.0325
		GOTERM_MF	GO:0000981∼RNA polymerase II transcription factor activity, sequence-specific DNA binding	0.0448
	Hyper	UniProt_BP	KW-0119∼Carbohydrate metabolism	0.00340

BP; biological process, MF; molecular functions.