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. 2023 Aug 24;15:1219718. doi: 10.3389/fnagi.2023.1219718

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Copyright © 2023 Berezhnoy, Laske and Trautwein.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Overview of regression analysis oPLS-DA score and variables importance in projection (VIP) score plots of the serum metabolites between Alzheimer’s disease (AD), controls (Con) and mild cognitive impairment (MCI) (AD; n = 26, Con; n = 29, MCI; n = 21) in the serum cohort: (A–C) oPLS-DA and VIP score plots of the serum metabolites between the groups AD and Con, MCI and Con; AD and MCI. In the VIP scores plot each box is representing a group mean value in a form of color gradient (red – high concentration, blue – low concentration). AD, Alzheimer’s disease; MCI, mild cognitive impairment; Con, control subjects.