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. 2023 Aug 24;15:1219718. doi: 10.3389/fnagi.2023.1219718

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Copyright © 2023 Berezhnoy, Laske and Trautwein.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PatternHunter (Pearson correlation plots) for MMSE (A), ApoE4 (B) with NMR-based metabolomics in blood serum when comparing Alzheimer’s disease (AD) with controls (Con) and mild cognitive impairment (MCI): Each plot is a graphical representation of the top 25 other variables that were displaying the highest absolute correlation values (both positive, up to 1.0, and negative, down to –1.0). Correlations from the study were highlighted (positive correlations marked red, negative – blue). MMSE, mini-mental state exam. ApoE-4 – amount of (0–2 copies) of the apoE-4 allele.