Supplementary Table 3:
NT-3 genotype variants in schizophrenia cases with mild, moderate, marked, and severe illness.
| Genotype | Schizophrenia with mild illness (PANSS: 30–58) (n=107) (%) |
Schizophrenia with moderate illness (PANSS: 59–74) (n=54) (%) |
Schizophrenia with marked illness (PANSS: 75-94) (n=37) (%) |
Schizophrenia with severe illness (PANSS: >95) (n=18) (%) |
P-value |
|---|---|---|---|---|---|
| rs6489630 | |||||
| CC | 60 (56) | 22 (40.7) | 17 (46) | 6 (33.3) | 0.004 |
| CT | 37 (34.5) | 32 (59.3) | 18 (48.6) | 8 (44.4) | |
| TT | 10 (9.5) | 0 | 2 (5.4) | 4 (22.3) | |
| rs6332 | |||||
| GG | 38 (35.5) | 17 (32) | 6 (16) | 5 (27.7) | 0.452 |
| AG | 51 (47.7) | 28 (52) | 24 (65) | 11 (61.1) | |
| AA | 18 (16.8) | 9 (16) | 7 (19) | 2 (11.2) | |
| rs1063714 | |||||
| AG | 95 (88.8) | 48 (89) | 28 (75.7) | 13 (72.3) | 0.08 |
| GG | 12 (11.2) | 6 (11) | 9 (24.3) | 5 (27.7) | |
NT-3: Neurotrophin-3, PANSS: Positive and negative symptom scores