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. 2023 Aug 24;14:1207075. doi: 10.3389/fphar.2023.1207075

TABLE 4.

Results of pairwise meta-analyses for the BI score.

Comparative Reference medications Number of studies Number of controls Number of patients MD/OR 95% CI I2 p
Nimodipine Placebo 2 76 78 2.29 [-17.45, 22.03] 0 0.38
Citicoline Placebo 1 60 60 3.36 [2.80, 3.93] 0 0.00001
Oxiracetam Placebo 4 172 172 2.24 [0.37, 4.11] 0 0.032
NBP Placebo 2 88 88 13.53 [9.84, 17.22] 0 0.014
Donepezil Placebo 2 79 79 1.48 [1.13, 1.83] 0 0.0001
Salvianolate Placebo 11 769 773 7.69 [5.15, 10.21] 0 0.00001
TCM Placebo 5 200 200 12.36 [8.79, 15.92] NA 0.07
Olacetam Placebo 5 211 208 8.71 [17.19, 20.24] 0 0.01

CI, confidence interval; MD, mean difference; OR, risk ratio; I2, heterogeneity; TCM, traditional chinese medicine; NBP, DL-3-n-Butylphthalide.