Table 3. Postdiagnosis Logistic Regression Models for Psychotic Disorder and Nonpsychotic Bipolar Disorder.
| Exposures | OR (95% CI) | |||||
|---|---|---|---|---|---|---|
| Psychotic disorder | Nonpsychotic bipolar disorder | |||||
| Univariable model | Bivariable modela | Multivariable modelb | Univariable model | Bivariable modela | Multivariable modelb | |
| Deprivation index | ||||||
| Trajectory 1 (least deprived) | 1 [Reference] | 1 [Reference] | 1 [Reference] | 1 [Reference] | 1 [Reference] | 1 [Reference] |
| Trajectory 2 | 1.00 (0.91-1.09) | 1.03 (0.94-1.12) | 1.02 (0.93-1.12) | 1.04 (0.96-1.13) | 1.04 (0.96-1.14) | 1.04 (0.95-1.14) |
| Trajectory 3 | 1.03 (0.94-1.12) | 1.07 (0.98-1.17) | 1.04 (0.95-1.14) | 1.16 (1.06-1.26) | 1.16 (1.07-1.26) | 1.11 (1.02-1.21) |
| Trajectory 4 | 1.23 (1.13-1.34) | 1.27 (1.16-1.38) | 1.19 (1.09-1.30) | 1.28 (1.18-1.39) | 1.29 (1.19-1.40) | 1.21 (1.11-1.32) |
| Trajectory 5 (most deprived) | 1.55 (1.43-1.69) | 1.57 (1.44-1.70) | 1.36 (1.24-1.48) | 1.51 (1.39-1.64) | 1.52 (1.40-1.65) | 1.39 (1.28-1.51) |
| Trajectory 6 (downward drift) | 1.29 (1.09-1.53) | 1.28 (1.08-1.51) | 1.38 (1.16-1.65) | 1.28 (1.03-1.57) | 1.28 (1.04-1.58) | 1.06 (0.85-1.33) |
| Trajectory 7 (upward mobility) | 0.85 (0.80-0.91) | 0.86 (0.70-1.06) | 0.91 (0.74-1.13) | 1.29 (1.01-1.65) | 1.30 (1.01-1.67) | 1.11 (0.86-1.44) |
| Population density | ||||||
| Trajectory 1 (least densely populated) | 1 [Reference] | 1 [Reference] | 1 [Reference] | 1 [Reference] | 1 [Reference] | 1 [Reference] |
| Trajectory 2 | 1.25 (1.14-1.36) | 1.25 (1.14-1.36) | 1.21 (1.10-1.32) | 1.03 (0.95-1.11) | 1.03 (0.95-1.12) | 1.02 (0.93-1.11) |
| Trajectory 3 | 1.34 (1.24-1.45) | 1.33 (1.23-1.44) | 1.27 (1.18-1.38) | 1.02 (0.95-1.09) | 1.02 (0.95-1.10) | 0.99 (0.91-1.07) |
| Trajectory 4 (most densely populated) | 1.35 (1.26-1.45) | 1.26 (1.17-1.36) | 1.15 (1.07-1.25) | 1.06 (0.99-1.14) | 1.01 (0.94-1.08) | 0.97 (0.90-1.04) |
| Trajectory 5 (urban-rural movement) | 1.15 (0.94-1.40) | 1.13 (0.93-1.39) | 1.15 (0.93-1.42) | 1.06 (0.85-1.32) | 0.99 (0.79-1.24) | 0.87 (0.69-1.10) |
| Parental migrant status | 1.73 (1.63-1.84) | NA | 1.51 (1.41-1.61) | 1.12 (1.05-1.19) | NA | 1.03 (0.97-1.10) |
| Parental history of SMI | 3.94 (3.52-4.40) | NA | 3.47 (3.10-3.88) | 4.28 (3.86-4.75) | NA | 3.86 (3.47-4.29) |
| Parental disposable income at birth | ||||||
| 1 (Lowest quintile) | 1 [Reference] | NA | 1 [Reference] | 1 [Reference] | NA | 1 [Reference] |
| 2 | 0.72 (0.67-0.78) | NA | 0.82 (0.76-0.89) | 0.95 (0.88-1.02) | NA | 1.05 (0.97-1.13) |
| 3 | 0.64 (0.59-0.69) | NA | 0.79 (0.73-0.86) | 0.85 (0.79-0.91) | NA | 0.99 (0.92-1.07) |
| 4 | 0.66 (0.61-0.71) | NA | 0.85 (0.78-0.92) | 0.73 (0.68-0.79) | NA | 0.90 (0.83-0.97) |
| 5 (Highest quintile) | 0.63 (0.58-0.68) | NA | 0.83 (0.76-0.90) | 0.79 (0.73-0.85) | NA | 1.01 (0.93-1.10) |
| Moves between birth and 14th year | 1.21 (1.19-1.24) | NA | 1.17 (1.15-1.19) | 1.21 (1.19-1.23) | NA | 1.17 (1.15-1.19) |
| Moves between diagnosis and end of follow-up | 0.97 (0.95-0.99) | NA | 0.95 (0.94-0.97) | 1.08 (1.06-1.09) | NA | 1.06 (1.04-1.08) |
Abbreviations: NA, not applicable; OR, odds ratio; SMI, severe mental illness.
a
Adjusted for deprivation index and population density trajectory membership and controlling for birth year and sex by matching cases and controls.
b
Adjusted as in the bivariable model and for parental migrant status, parental history of SMI, parental disposable income at birth, number of moves between birth and 14th year, and number of moves between diagnosis and end of follow-up.