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. Author manuscript; available in PMC: 2023 Sep 7.
Published in final edited form as: Inflamm Res. 2015 Nov 25;65(1):71–80. doi: 10.1007/s00011-015-0892-z

Figure 4. Rat TBECs inactivate influenza virions in a Duox/H2O2/LPO/SCN−-dependent manner.

Figure 4.

ALI cultures of differentiated primary Sprague-Dawley rat TBECs were exposed to 8000 PFU of H1N2 IAV (swH1N2) in presence or absence of ATP (Duox activator, 100 μM), LPO (6.5 μg/ml) or SCN− (400 μM) in the indicated combinations. After 1 hr incubation supernatants were collected and concentration of viable virus particles was determined by PFU assay using MDCK cells. Mean+/−S.E.M., n=4. ANOVA, Brown-Forsythe test, Tukey’s multiple comparisons. *, p<0.05; **, p<0.01. IAV, influenza A virus; PFU, plaque forming unit.