TABLE 2.

Drug activities against five clinical isolates of L. pneumophila SG1^a

Drug	MIC range (μg/ml)b	MIEC range (μg/ml)c
Ceftizoxime	0.125–0.5	>64
Erythromycin	0.063–0.5	1.0–4.0
Azithromycin	0.031–0.5	0.5–4.0
Roxithromycin	0.125–0.5	0.25–0.5
Clarithromycin	0.031–0.063	0.031–0.063
Levofloxacin	0.031–0.063	0.016
Ciprofloxacin	0.016–0.031	0.016–0.063
Sparfloxacin	0.004	0.002–0.004

^aThe MICs and MIEC for five clinical isolates (isolates 80-045, 90-001, 90-002, 93-001, and 97-001) were evaluated. 

^bMICs were determined by the microdilution method in BYE-α broth, and the inoculum size was 10⁶ CFU/ml. 

^cThe MIECs represent the intracellular antimicrobial activity and were determined by the methods described in the text.