Fig. 2.

The Mutation Variant Frequency Change (MVFC) patterns of plasma and tumor mutations during surgical operations in the exploration dataset. (A) Variant allele frequency distribution of detected plasma mutations in pre‐operative plasma and tumor mutations identified from tumor tissues. (B) Variant types and SNV substitution distribution of detected plasma mutations. (C) The variant frequency change of plasma mutations between pre‐ and post‐operative plasma samples. (D) The distributions of Mutation Variant Frequency Change (MVFC) of plasma mutations. Plasma mutations were categorized into two types according to MVFC (threshold 0.2) and colored differently. (E) The variant frequency change of tumor mutations identified from tumor tissue between pre‐ and post‐operative plasma samples. (F) The distributions of Mutation Variant Frequency Change (MVFC) of tumor mutations identified from tumor tissue. Tumor mutations were categorized into two types according to MVFC (threshold 0.2) and colored differently. MVFC, Mutation Variant Frequency Change; SNV, single nucleotide variant; VAF, Variant allele frequency.