Table 2.
Patient characteristics on ICU admission.
| Characteristics | Total cohort | ADVOS | OPAL | MARS | SPAD | p-value |
|---|---|---|---|---|---|---|
| N | 96 | 52 | 14 | 13 | 17 | |
| Age, year | ||||||
| Median (IQR) | 54 [44.0–64.0] | 60 [49.5–65.8] | 48 [44.8–58.5] | 51 [38.0–64.5] | 60 [50.0–68.5] | n.s. |
| Minimum/maximum | 20.0/82.0 | 20.0/82.0 | 26.0/64.0 | 28.0/70.0 | 44.0/76.0 | |
| Male sex, n (%) | 60 (62.5) | 34 (65.4) | 7 (50.0) | 8 (61.5) | 11 (64.7) | n.s. |
| Outcome, n (%) | ||||||
| ICU mortality | 61 (63.5) | 37 (71.2) | 7 (50.0) | 6 (46.2) | 11 (64.7) | n.s. |
| Hospital survival | 26 (27.1) | 10 (19.2) | 5 (35.7) | 7 (53.8) | 4 (23.5) | |
| Scores at admission ICU, median (IQR) | ||||||
| MELD | 33 [22.5–38.0] | 31 [17.0–40.0] | 32 [28.0–35.8] | 32 [21.8–35.0] | 35 [23.3–40.0] | n.s. |
| APACHE II | 25 [20.0–29.3] | 25 [20.0–32.0] | 23 [20.5–27.3] | 26 [19.5–30.0] | 25 [21.3–30.0] | n.s. |
| SAPS II | 50 [41.8–62.3] | 50 [43.0–61.0] | 50 [39.0–57.8] | 49 [39.5–65.0] | 52 [41.0–68.3] | n.s. |
| SOFA | 12 [9.0–16.0] | 13 [9.0–16.0] | 12 [9.8–17.3] | 12 [10.5–14.0] | 12 [7.0–15.5] | n.s. |
| RRT during the first 24 h of ICU admission, n (%) | 56 (58.3) | 23 (44.2) | 6 (42.9) | 6 (46.2) | 8 (47.1) | n.s. |
| Liver failure, n (%) | ||||||
| Primary liver failure | 71 (74.0) | 40 (76.9) | 10 (71.4) | 10 (76.9) | 11 (64.7) | n.s. |
| Secondary liver failure | 25 (26.0) | 12 (23.1) | 4 (28.6) | 3 (23.1) | 6 (35.3) | |
| Number of treatments | ||||||
| Median (IQR) | 3 [1.0–4.8] | 3 [1.0–5.0] | 3 [2.8–8.3] | 2 [1.0–3.0] | 2 [1.0–3.5] | n.s. |
| Minimum/maximum | 1/17 | 1/17 | 1/12 | 1/10 | 1/10 | |
ICU: intensive care unit; APACHE II: Acute Physiology and Chronic Health Evaluation II; SAPS II: Simplified Acute Physiology Score II; SOFA: Sequential Organ Failure Assessment; RRT: renal replacement therapy; n.s.: no significance.