Table 1.
Characteristics of Patients With CON and NTG
| CON | NTG | P * | |
|---|---|---|---|
| Eyes, n | 56 | 71 | N/A |
| Age (y), mean ± SD | 52.7 ± 11.5 | 53.2 ± 8.4 | 0.827 |
| Gender (male/female), n | 31/25 | 32/38 | 0.372 |
| SE (D), mean ± SD | −1.49 ± 2.45 | −2.38 ± 2.19 | 0.177 |
| IOP at examination (mmHg), mean ± SD | 16.0 ± 5.3 | 14.0 ± 2.9 | 0.013 |
| MD (dB), mean ± SD | −4.60 ± 5.13 | −6.78 ± 4.81 | 0.063 |
| PSD (dB), mean ± SD | 6.11 ± 5.25 | 10.83 ± 5.04 | <0.001 |
| Hemifield involvement, n (%) | N/A | Inferior, 43 (61.4) | N/A |
| Superior, 4 (5.7) | |||
| Both, 23 (32.9) | |||
| OCT, Mean ± SD | |||
| Average peripapillary RNFL thickness (µm) | 77.4 ± 9.4 | 74.5 ± 8.3 | 0.092 |
| Superior | 97.6 ± 15.1 | 97.3 ± 17.9 | 0.919 |
| Temporal | 51.8 ± 10.1 | 62.1 ± 10.0 | 0.001 |
| Inferior | 101.8 ± 16.6 | 72.5 ± 14.6 | <0.001 |
| Nasal | 59.0 ± 8.5 | 64.4 ± 9.1 | 0.018 |
| Average GCIPL thickness (µm) | 67.0 ± 5.5 | 68.0 ± 4.6 | 0.359 |
| Minimum GCIPL thickness (µm) | 55.6 ± 8.9 | 51.6 ± 4.8 | 0.015 |
| Sectoral GCIPL thickness (µm) | |||
| Superior | 64.8 ± 7.0 | 76.6 ± 8.7 | <0.001 |
| Superotemporal | 76.3 ± 7.6 | 73.2 ± 7.2 | 0.032 |
| Inferotemporal | 79.6 ± 8.0 | 55.3 ± 6.8 | <0.001 |
| Inferior | 66.8 ± 6.7 | 56.0 ± 6.0 | <0.001 |
| Inferonasal | 55.7 ± 8.0 | 67.2 ± 7.7 | <0.001 |
| Superonasal | 57.8 ± 8.7 | 79.9 ± 8.1 | <0.001 |
| OCTA, Mean ± SD | |||
| Average peripapillary VD (%) | 51.6 ± 4.6 | 55.1 ± 3.8 | <0.001 |
| Superior | 58.9 ± 8.1 | 62.5 ± 6.5 | 0.012 |
| Temporal | 38.7 ± 5.7 | 52.7 ± 8.1 | <0.001 |
| Inferior | 65.6 ± 8.5 | 51.3 ± 9.7 | <0.001 |
| Nasal | 43.4 ± 6.4 | 53.8 ± 5.5 | <0.001 |
| Average macular VD (%) | 46.5 ± 2.6 | 47.3 ± 2.8 | 0.233 |
| Superior | 47.4 ± 2.9 | 49.4 ± 4.9 | 0.174 |
| Temporal | 46.9 ± 2.8 | 46.4 ± 3.5 | 0.341 |
| Inferior | 47.3 ± 3.5 | 45.6 ± 4.6 | 0.032 |
| Nasal | 44.4 ± 3.8 | 47.7 ± 6.1 | 0.147 |
CON, compressive optic neuropathy; NTG, normal-tension glaucoma; N/A, not applicable; SE, spherical equivalent; IOP, intraocular pressure; MD, mean deviation; PSD, pattern standard deviation; OCT, optical coherence tomography; RNFL, retinal nerve fiber layer; GCIPL, ganglion cell inner plexiform layer; OCTA, optical coherence tomography angiography; VD, vessel density. Bold text denotes statistical significance.
*
P values were calculated using a generalized estimation equation (GEE).