Table 3.
Associations between abnormal BMI and HRQoL impairments at week 52.
| BMI categories | ||||
|---|---|---|---|---|
| Normal weight (N = 838) |
Underweight (N = 72) |
Pre-obese (N = 432) |
Obese (N = 323) |
|
| EQ-5D mobility | ||||
| Level 2 + Level 3 | 218 + 5 = 223 (26.6%) |
13 + 2 = 15 (20.8%) |
163 + 5 = 168 (38.9%) |
152 + 0 = 152 (47.1%) |
| Unadj. OR (95% CI) | Ref. | 0.75 (0.39–1.40); p = 0.382 |
1.63 (1.24–2.15);
p < 0.001 |
1.82 (1.35–2.45);
p < 0.001 |
| Adj. OR (95% CI) | Ref. | 0.92 (0.46–1.73); p = 0.796 |
1.47 (1.10–1.96);
p = 0.009 |
1.42 (1.03–1.96);
p = 0.031 |
| EQ-5D self-care | ||||
| Level 2 + Level 3 | 100 + 5 = 105 (12.5%) |
10 + 2 = 12 (16.7%) |
82 + 3 = 85 (19.7%) |
69 + 3 = 72 (22.3%) |
| Unadj. OR (95% CI) | Ref. | 1.46 (0.67–2.97); p = 0.317 |
1.63 (1.14–2.33);
p = 0.007 |
1.55 (1.05–2.27);
p = 0.026 |
| Adj. OR (95% CI) | Ref. | 1.67 (0.75–3.47); p = 0.187 |
1.52 (1.05–2.19);
p = 0.027 |
1.27 (0.84–1.91); p = 0.236 |
| EQ-5D usual activities | ||||
| Level 2 + Level 3 | 306 + 16 = 322 (38.4%) |
24 + 2 = 26 (36.1%) |
191 + 16 = 207 (47.9%) |
175 + 10 = 185 (57.3%) |
| Unadj. OR (95% CI) | Ref. | 1.03 (0.59–1.78); p = 0.913 |
1.39 (1.07–1.80);
p = 0.013 |
1.61 (1.21–2.14);
p = 0.001 |
| Adj. OR (95% CI) | Ref. | 1.23 (0.70–2.15); p = 0.468 |
1.22 (0.93–1.60); p = 0.158 |
1.18 (0.87–1.61); p = 0.284 |
| EQ-5D pain/discomfort | ||||
| Level 2 + Level 3 | 493 + 46 = 539 (64.3%) |
40 + 4 = 44 (61.1%) |
273 + 29 = 302 (69.9%) |
232 + 34 = 266 (82.4%) |
| Unadj. OR (95% CI) | Ref. | 0.80 (0.47–1.37); p = 0.399 |
1.12 (0.860–1.47); p = 0.396 |
2.07 (1.49–2.92);
p < 0.001 |
| Adj. OR (95% CI) | Ref. | 0.92 (0.53–1.59); p = 0.749 |
0.99 (0.75–1.30); p = 0.914 |
1.53 (1.08–2.20);
p = 0.018 |
| EQ-5D anxiety/depression | ||||
| Level 2 + Level 3 | 332 + 40 = 372 (44.4%) |
30 + 4 = 34 (47.2%) |
189 + 17 = 206 (47.7%) |
144 + 25 = 169 (52.3%) |
| Unadj. OR (95% CI) | Ref. | 1.34 (0.77–2.32); p = 0.296 |
1.11 (0.86–1.45); p = 0.426 |
1.29 (0.97–1.73); p = 0.084 |
| Adj. OR (95% CI) | Ref. | 1.45 (0.83–2.54); p = 0.189 |
1.04 (0.79–1.37); p = 0.767 |
1.12 (0.82–1.53); p = 0.471 |
Data are presented as numbers (percentage). In case of missing data, the number of available observations is indicated with N. P-values were derived from logistic regression analysis. P-values < 0.05 are in bold. Adj., adjusted; BMI, body mass index; CI, confidence interval; HRQoL, health-related quality of life; OR, odds ratio; Ref, reference; Unadj., unadjusted.