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. 2023 Aug 24;15:1243588. doi: 10.3389/fnagi.2023.1243588

Table 2.

The quality assessment of included studies.

Study (cohort) Representativeness of exposed cohort (1) Selection of non-exposed cohort (1) Ascertainment of exposure (1) Outcome not present before study (1) Comparability (2) Assessment of outcome (1) Follow-up long enough (1) Adequacy of follow up*(1) Quality score
Gofrit et al. (2019a) ** 9
Klinger et al. (2021) ** 9
Kim et al. (2021) ** 9
Makrakis et al. (2022) ** 9
Weinberg et al. (2023) ** 9

Follow-up period (median, ≥3 years; or maximum, ≥5 years) was considered enough. The quality of studies were assessed using the Newcastle–Ottawa (NOS) scale. The NOS scale is a star rating system that allocates a maximum of nine stars across three categories: participant selection (four stars; the first four columns, Column 2–5), comparability (two stars; Column 6) and measurement of outcome in cohort (three stars; Column 7–9). At last, the score (Column 10) of each study was calculated based on the summary. In addition, a high score means a low bias risk.