Table 2.
List of top ten up- and down-regulated differentially expressed genes in colon cancer and normal tissue.
| Gene | p-Value | p-Adj | Log2FC | Description | |
|---|---|---|---|---|---|
| Up | PLVAP | 2.52E-111 | 6.97E-107 | 3.002353 | plasmalemma vesicle associated protein |
| COL15A1 | 1.26E-90 | 1.74E-86 | 4.023823 | collagen type XV alpha 1 chain | |
| GABRD | 3.05E-88 | 2.81E-84 | 4.507174 | gamma-aminobutyric acid type A receptor subunit delta | |
| GPC3 | 2.33E-82 | 1.61E-78 | 6.061433 | glypican 3 | |
| THBS4 | 4.98E-78 | 2.29E-74 | 5.593584 | thrombospondin 4 | |
| DIPK2B | 7.57E-75 | 2.99E-71 | 2.301232 | divergent protein kinase domain 2B | |
| SLC26A6 | 1.27E-74 | 4.39E-71 | 2.598325 | solute carrier family 26 member 6 | |
| CDKN3 | 2.48E-74 | 7.62E-71 | 3.725304 | cyclin dependent kinase inhibitor 3 | |
| FOXM1 | 1.17E-72 | 3.23E-69 | 3.231552 | forkhead box M1 | |
| NUF2 | 2.19E-72 | 5.50E-69 | 3.854367 | NUF2 component of NDC80 kinetochore complex | |
| Down | ADAMTS13 | 1.38E-81 | 7.63E-78 | -2.70486 | ADAM metallopeptidase with thrombospondin type 1 motif 13 |
| OIT3 | 6.41E-72 | 1.26E-68 | -3.10719 | oncoprotein induced transcript 3 | |
| STAB2 | 4.16E-67 | 4.79E-64 | -4.43614 | stabilin 2 | |
| ECM1 | 1.75E-57 | 1.10E-54 | -3.08879 | extracellular matrix protein 1 | |
| MAP2K1 | 2.27E-55 | 1.08E-52 | -1.33004 | mitogen-activated protein kinase kinase 1 | |
| CCL23 | 4.26E-55 | 1.96E-52 | -2.87074 | C-C motif chemokine ligand 23 | |
| BMPER | 4.82E-52 | 1.73E-49 | -4.41371 | BMP binding endothelial regulator | |
| TRIB1 | 1.33E-51 | 4.61E-49 | -1.99208 | tribbles pseudokinase 1 | |
| PTH1R | 1.68E-50 | 5.00E-48 | -3.26794 | parathyroid hormone 1 receptor | |
| LYVE1 | 5.70E-50 | 1.56E-47 | -3.28161 | lymphatic vessel endothelial hyaluronan receptor 1 |