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. 2023 Sep 7;52(9):afad163. doi: 10.1093/ageing/afad163

Table 2.

Insomnia symptoms and incidence rate of dementia.

Exposure N of dementia incidence (% in group) Model 1 Model 2
HR (95% CI) P HR (95% CI) P
Status of insomnia symptoms
Non-insomnia 1,100 (6.0) 1 1
Have insomnia symptom 287 (7.9) 1.28 (1.12, 1.46) <0.001 1.18 (1.03, 1.35) 0.018
Symptom of insomnia
Non-insomnia 1,100 (6.0) 1 1
Other symptoms than DIS 172 (7.0) 1.20 (1.02, 1.41) 0.028 1.12 (0.95, 1.32) 0.173
DIS 115 (9.5) 1.40 (1.15, 1.70) 0.001 1.24 (1.02, 1.52) 0.031
Non-insomnia 1,100 (6.0) 1 1
Other symptoms than DMS 132 (7.6) 1.33 (1.11, 1.59) 0.002 1.25 (1.04, 1.50) 0.017
DMS 155 (8.1) 1.24 (1.05, 1.47) 0.013 1.11 (0.94, 1.33) 0.221
Non-insomnia 1,100 (6.0) 1 1
Other symptoms than EMA 133 (8.9) 1.36 (1.14, 1.63) 0.001 1.25 (1.04, 1.51) 0.016
EMA 154 (7.1) 1.21 (1.02, 1.43) 0.030 1.11 (0.93, 1.32) 0.248

Analysed by Cox proportional hazards regression. Model 1, adjusted for age and sex; Model 2, adjusted for Model 1 and education level, depression, social isolation, body mass index, level of physical activity, smoking status, alcohol consumption, hypertension and diabetes.