Table 1 Patient demographics and baseline chracteristiscs of the FAS.

	0.23 mg/kg/week (n=59)	0.46 mg/kg/week (n=58)	p-Value
Chronological age, years	4.77±1.16	4.66±1.27	0.626
Gender
Male, n (%)	36 (61.02)	35 (60.34)	0.941
Female, n (%)	23 (38.98)	23 (39.66)
Ethnicity
Han (%)	58 (98.31)	57 (92.28)	1.000
Others (%)	1 (1.69)	1 (1.72)
Birth length, cm	46.1±3.5	46.5±2.8	0.593
Birth length, SDS a	–0.08±0.07	–0.07±0.05	0.577
Birth weight, kg	2.20±0.31	2.30±0.29	0.087
Birth weight, SDS a	–2.29±0.09	–2.27±0.08	0.086
Head circumference at birth, cm	29.4±3.1	30.5±2.9	0.168
Parental height, cm
Father	168.3±6.7	167.9±6.1	0.749
Mother	156.0±6.3	155.3±5.3	0.527
Parental height, SDS b
Father	–0.02±0.04	–0.03±0.03	0.749
Mother	–0.03±0.04	–0.03±0.03	0.527
Genetic target height, cm	163.6±7.7	163.1±7.2	0.692
Pituitary gland MRI, n (%)
Normal	46 (83.64)	47 (82.46)	0.868
Abnormal	9 (16.36)	10 (17.54)
HT-SDS	–2.77±1.14	–2.89±1.11	0.580
Height, cm	95.6±7.9	94.2±9.8	0.410
BA, years	3.04±1.04	2.91±1.10	0.497
IGF-1, ng/ml	95.25±43.27	78.90±50.42	0.064
IGF-1/IGFBP-3	0.10±0.03	0.09±0.04	0.043

BA: Bone age; FAS: Full analysis set; HT-SDS: Height SD score; IGFBP-3: IGF binding protein-3; MRI: Magnetic resonance imaging.; ^a Calculated using data of newborns from the 2005 physical development survey of children aged 0–18 years in nine cities in China as reference.; ^b Calculated using data of 18-year-olds from the 2005 physical development survey of children aged 0–18 years in nine cities in China as reference.