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. 2023 Jul 13;51(16):8643–8662. doi: 10.1093/nar/gkad589

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© The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — RAD54-GFP localization changes with TLK1 inhibition after IR (10 Gy). At 2 h IR recovery, RAD54-GFP is predominantly in nucleus (middle panel) and at 10 h after IR (lower panel) when HRR attenuates, RAD54-GFP re-localizes to cytoplasm. With TLK1 inhibition followed by IR and recovery for 2 h (2 h, +J54), RAD54GFP localizes in nucleus. At increased time of IR recovery (10 h, +J54) with TLK1 inhibition, RAD54GFP re-localization to cytoplasm is hindered. Control panel shows RAD54-GFP localization in non-irradiated cells. Images acquired from fixed cell microscopy with DAPI stained nucleus. Scale bar is 20 μm.