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. 2023 Aug 4;54(3):1513–1521. doi: 10.1007/s42770-023-01071-6

Table 2.

Susceptibility testing of ciclopirox olamine-loaded conventional and stealth liposomes against C. neoformans clinical strains

Cryptococcus neoformans clinical strains CPO-LipoC CPO-LipoS
MIC MFC MIC MFC
mg/L mg/L
URM 5809 2 8 2 8
URM 5810 1 2 1 2
URM 5811 1 1 1 1
URM 5812 1 2 1 2
URM 5813 1 1 1 1
URM 5814 1 2 1 2
URM 5815 1 2 1 2
URM 5816 1 2 1 2
URM 5818 1 8 1 8
URM 5819 2 8 2 8
URM 5820 1 2 1 2
URM 5821 1 8 1 8
URM 5822 2 8 2 8
URM 5823 2 8 2 8
URM 5824 1 1 1 1
URM 5825 1 1 1 1
URM 117 2 2 2 2
URM 123 1 2 1 2
URM 124 1 1 1 1
URM 125 1 2 1 2
URM 126 1 2 1 2
URM 127 1 2 1 2
URM 128 1 2 1 2
URM 129 2 2 2 2
URM 131 2 2 2 2
URM 132 2 4 2 4
URM 144 2 4 2 4
URM 150 1 2 1 2
URM 151 1 2 1 2
URM 155 1 2 1 2
URM 156 2 2 2 2
URM 157 1 2 1 2

CPO-LipoC, ciclopirox olamine-loaded conventional liposomes; CPO-LipoS, ciclopirox olamine-loaded stealth liposomes; MIC, minimum inhibitory concentration; MFC, minimum fungicidal concentration