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. 2023 Sep 7;13:14752. doi: 10.1038/s41598-023-38843-x

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Forest plot quantifying skeletal muscle SIRT1 gene expression (measured via qPCR or RT-PCR) following a single bout of high-intensity exercise. Adjusted standardised mean difference (Hedges’ g), relative weight of each acute study response, confidence interval (diamond), and prediction interval (blue line) are also shown. HIA high-intensity aerobic, HIIT high-intensity interval training, OM old men, M men, SIT sprint interval training, W women, YM young men. Percentages denote proportion of exercise intensity. n = sample size.