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. 2023 Mar 2;18(1-2):145–159. doi: 10.1007/s11481-023-10059-w

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Signalling pathway alterations in neuronal cells upon mediator treatment. Regulation of signalling pathway-specific target genes in neuronal cells after 24 h of treatment with individual proinflammatory mediators (x-axis: IL-17A, TNFα, IFNγ and combination of IL-17A/TNFα, IL-17A/IFNγ and TNFα/IFNγ (concentration: 50 ng/mL)) in comparison to untreated cells as assessed with rt-qPCR arrays (y-axis: respective pathway-specific target genes). Colours quantify RQ in gene expression. Rt-qPCR arrays were performed twice with independent samples (pooled data shown)