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. 2023 Feb 13;18(1-2):195–207. doi: 10.1007/s11481-023-10060-3

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Effect of alirocumab (Aliro-L,Aliro-M and Aliro-H) on CUMS-induced behavioral Changes in rats in: a–h open-field test and i–k Forced swimming test; a Number of total crossed squares, b Number of central zone entries, c Latency to leave the central zone, d Central zone duration, e Frequency of rearing, f Frequency of grooming, g Mean velocity, h Total distance travelled, i Swimming time, j Struggling, k Immobility time. ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 vs. control group and ^*P < 0.05, ^**P < 0.01 vs. CUMS group; by one-way ANOVA followed by Bonferroni post-hoc test

Fig. 2 — Effect of alirocumab (Aliro-L,Aliro-M and Aliro-H) on CUMS-induced behavioral Changes in rats in: a–h open-field test and i–k Forced swimming test; a Number of total crossed squares, b Number of central zone entries, c Latency to leave the central zone, d Central zone duration, e Frequency of rearing, f Frequency of grooming, g Mean velocity, h Total distance travelled, i Swimming time, j Struggling, k Immobility time. ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 vs. control group and ^*P < 0.05, ^**P < 0.01 vs. CUMS group; by one-way ANOVA followed by Bonferroni post-hoc test