Figure 6.

Cholesterol converter type-specific dietary impact on serum lipids

(A and B) Decreased serum TAG levels in both cholesterol low-converters (A, N[PRE] = 37, N[LCHF] = 11) and high-converters (B, N[PRE] = 106, N[LCHF] = 43), based on estimated marginal means (EMMs), as determined by the GLMM for the combined KETO and CARBFUNC cohorts.

(C) Increased serum LDL-C levels in lean cholesterol high-converters from the KETO study on the LCHF diet (N[PRE] = 17, N[LCHF] = 18). Individuals were classified as cholesterol high/low-converters based on pre-intervention time points, with symbol colors indicating the classification during the LCHF diet. Significance determined by GLMM and post-hoc Tukey’s test (Benjamini-Hochberg-corrected): q > 0.1 ns, q < 0.1 ∗, q < 0.05 ∗∗, q < 0.01 ∗∗∗, q < 0.001 ∗∗∗∗. Pooled data are represented as mean ± SD.