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. 2023 Apr 24;28(9):e712–e722. doi: 10.1093/oncolo/oyad086

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© The Author(s) 2023. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Left ventricular ejection fraction (LVEF) and global longitudinal strain (GLS) in patients without cardiac-dose limiting toxicity (cDLT). The graphs show trend in left ventricular ejection fraction (a) and global longitudinal strain (b, scale reversed for ease of interpretation) in patients without cDLT (n = 47) in the study. Bars represent percent of patients on trastuzumab at each time point. Table accompanying each graph shows the number of patients who demonstrated normalized LVEF (≥54%) or normalized GLS (≤−17% or to baseline level) at each time point. P-values represent the comparison of LVEF or GLS with baseline values at selected time points.