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. 2023 Apr 10;28(9):e823–e834. doi: 10.1093/oncolo/oyad059
Patient Characteristics [Dose-Escalation Phase Ib Part]
Number of patients, male 4
Number of patients, female 6
Stage Stage IV (100%)
Age: median (range) 62 (48-67) years
Number of prior systemic therapies: median (range) 2.5 (1-4)
Performance status: ECOG 0: 2
1: 8
2: 0
3: 0
4: 0
Cancer types or histologic subtypes Stomach cancer (adenocarcinoma): 5 [PTEN (−) by IHC, n = 2; HER2 (+), n = 2]
Colorectal cancer (adenocarcinoma): 5 [PTEN (−) by IHC, n = 1]