Title |
Efficacy in the phase Ib part |
Number of patients screened |
10 |
Number of patients enrolled |
10 |
Number of patients evaluable for toxicity |
10 |
Number of patients evaluated for efficacy |
9 |
Evaluation method |
RECIST 1.1 |
Response assessment, CR |
0 (0%) |
Response assessment, PR |
2 (22.2%) |
Response assessment, SD |
1 (11.1%) |
Response assessment, PD |
6 (66.7%) |
(Median) duration assessments, PFS |
1.8 months (95% CI: 0.9-5.3) |
(Median) duration assessments, TTP |
1.8 months (95% CI: 0.9-5.3) |
(Median) duration assessments, OS |
4.7 months (95% CI: 2.6-21.4) |
Response duration |
1.5 months and 3.6 months, respectively |
(Median) duration of treatment |
1.3 months (range: 0.2-5.3 months) |