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. 2023 Apr 10;28(9):e823–e834. doi: 10.1093/oncolo/oyad059
Primary Assessment Method [Dose-Escalation Phase Ib Part]
Title Efficacy in the phase Ib part
Number of patients screened 10
Number of patients enrolled 10
Number of patients evaluable for toxicity 10
Number of patients evaluated for efficacy 9
Evaluation method RECIST 1.1
Response assessment, CR 0 (0%)
Response assessment, PR 2 (22.2%)
Response assessment, SD 1 (11.1%)
Response assessment, PD 6 (66.7%)
(Median) duration assessments, PFS 1.8 months (95% CI: 0.9-5.3)
(Median) duration assessments, TTP 1.8 months (95% CI: 0.9-5.3)
(Median) duration assessments, OS 4.7 months (95% CI: 2.6-21.4)
Response duration 1.5 months and 3.6 months, respectively
(Median) duration of treatment 1.3 months (range: 0.2-5.3 months)