Table 2. Agonist Dependence of DQP Analogues on GluN1/GluN2D NMDA Receptors^a.

	IC50, μM (95% CI)
	1 (DQP-1105)	(S)-2a	2i (DQP-997-74)
peak	1.4 (1.1, 1.7)	2.1 (1.6, 3.2)	0.23 (0.16, 0.32)
steady-state	0.72 (0.61, 0.84)	0.51 (0.39, 0.63)	0.08 (0.07, 0.09)
N	9	5	8
peak vs steady-state	F(1, 70) = 27, p < 0.001	F(1, 49) = 73, p < 0.001	F(1, 71) = 43, p < 0.001
pulse 1	4.9 (3.7, 6.5)	1.8 (1.3, 2.6)	0.75 (0.60, 0.94)
pulse 5	1.6 (1.3, 2.1)	0.75 (0.60, 0.94)	0.40 (0.32, 0.51)
N	7	8	8
pulse 1 vs pulse 5	F(1, 54) = 36, p < 0.001	F(1, 58) = 34, p < 0.001	F(1, 60) = 16, p = 0.002

^aN represents the number of cells. IC₅₀ value comparisons were made by extra sum-of-squares F tests.