Table S3. NRI of comparisons of MDCS and radiologists in pooled external and prospective testing sets.

Radiologist	Pooled external testing set			Prospective testing set
	IDI (95% CI)	P		NRI (95% CI)	P
NRI, net reclassification index; MDCS, multiprocess detection and classification system; IDI, integrated discrimination improvement; 95% CI, 95% confidence interval; R, radiologist.
R1	0.312 (0.188−0.406)	0.041		0.456 (0.335−0.491)	<0.001
R2	0.302 (0.196−0.411)	0.030		0.397 (0.139−0.370)	0.370
R3	0.246 (0.138−0.359)	0.122		0.237 (0.175−0.331)	0.026
R4	0.197 (−0.015−0.318)	0.076		0.294 (0.198−0.353)	<0.001
R5	0.045 (−0.003−0.202)	0.286		0.166 (0.082−0.246)	0.004
R6	0.164 (−0.005−0.339)	0.009		0.218 (0.151−0.281)	<0.001