Table S4. NRI of comparisons radiologists with or without MDCS assistance in pooled external and prospective testing sets.

Radiologist	Pooled external testing set			Prospective testing set
	IDI (95% CI)	P		NRI (95% CI)	P
NRI, net reclassification index; MDCS, multiprocess detection and classification system; 95% CI, 95% confidence interval; R, radiologist.
R1	0.164 (0.049−0.252)	0.041		0.211 (0.122−0.252)	0.006
R2	0.166 (0.066−0.209)	0.026		0.041 (−0.065−0.154)	<0.001
R3	0.045 (−0.032−0.089)	0.048		0.134 (0.095−0.245)	0.076
R4	0.112 (0.015−0.234)	<0.001		0.082 (0.027−0.110)	0.019
R5	0.031 (0.019−0.072)	0.107		0.014 (−0.068−0.094)	0.033
R6	0.097 (0.014−0.206)	<0.001		0.040 (−0.004−0.136)	0.162