Table 3.
Fifty-one novel SNP-CpG pairs in novel loci
| rsID | chr:position | CpG | Chra | Positiona | Beta* | p-value | function GVS | SNP Gene | CpG Gene | cis /trans |
|---|---|---|---|---|---|---|---|---|---|---|
| 34964576 | 1:43409364 | cg19693031 | 1 | 145441552 | 94.97 | 1.40E-10 | intron | SLC2A1 | TXNIP | trans |
| 35022307 | 1:43409420 | cg19693031 | 1 | 145441552 | 94.97 | 1.40E-10 | intron | SLC2A1 | TXNIP | trans |
| 751210 | 1:43410859 | cg19693031 | 1 | 145441552 | 94.97 | 1.40E-10 | intron | SLC2A1 | TXNIP | trans |
| 16830121 | 1:43412469 | cg19693031 | 1 | 145441552 | 95.49 | 1.18E-10 | intron | SLC2A1 | TXNIP | trans |
| 3768037 | 1:43412662 | cg19693031 | 1 | 145441552 | 95.49 | 1.18E-10 | intron | SLC2A1 | TXNIP | trans |
| 900836 | 1:43412727 | cg19693031 | 1 | 145441552 | 95.49 | 1.18E-10 | intron | SLC2A1 | TXNIP | trans |
| 7534555 | 1:43413319 | cg19693031 | 1 | 145441552 | 96.61 | 7.73E-11 | intron | SLC2A1 | TXNIP | trans |
| 7512557 | 1:43413324 | cg19693031 | 1 | 145441552 | 95.49 | 1.18E-10 | intron | SLC2A1 | TXNIP | trans |
| 7512565 | 1:43413361 | cg19693031 | 1 | 145441552 | 95.49 | 1.18E-10 | intron | SLC2A1 | TXNIP | trans |
| 710,222 | 1:43413653 | cg19693031 | 1 | 145441552 | 95.49 | 1.18E-10 | intron | SLC2A1 | TXNIP | trans |
| 61296119 | 1:43414046 | cg19693031 | 1 | 145441552 | 95.49 | 1.18E-10 | intron | SLC2A1 | TXNIP | trans |
| 74742820 | 1:43414369 | cg19693031 | 1 | 145441552 | 95.49 | 1.18E-10 | intron | SLC2A1 | TXNIP | trans |
| 57247989 | 1:43414370 | cg19693031 | 1 | 145441552 | 95.49 | 1.18E-10 | intron | SLC2A1 | TXNIP | trans |
| 75366795 | 1:43414447 | cg19693031 | 1 | 145441552 | 95.49 | 1.18E-10 | intron | SLC2A1 | TXNIP | trans |
| 112893098 | 1:43414563 | cg19693031 | 1 | 145441552 | 95.49 | 1.18E-10 | intron | SLC2A1 | TXNIP | trans |
| 2297975 | 1:43415516 | cg19693031 | 1 | 145441552 | 95.82 | 1.07E-10 | intron | SLC2A1 | TXNIP | trans |
| 79608798 | 1:43416158 | cg19693031 | 1 | 145441552 | 95.49 | 1.18E-10 | intron | SLC2A1 | TXNIP | trans |
| 4660691 | 1:43417150 | cg19693031 | 1 | 145441552 | 95.49 | 1.18E-10 | intron | SLC2A1 | TXNIP | trans |
| 12406072 | 1:43419737 | cg19693031 | 1 | 145441552 | 95.49 | 1.18E-10 | intron | SLC2A1 | TXNIP | trans |
| 113583149 | 1:43423955 | cg19693031 | 1 | 145441552 | 95.49 | 1.18E-10 | intron | SLC2A1 | TXNIP | trans |
| 11537640 | 1:43424519 | cg19693031 | 1 | 145441552 | 95.27 | 9.15E-11 | 5-prime-UTR | SLC2A1 | TXNIP | trans |
| 62621848 | 1:43425082 | cg19693031 | 1 | 145441552 | 95.49 | 1.18E-10 | non-coding-exon | SLC2A1-AS1 | TXNIP | trans |
| 4306169 | 1:43431433 | cg19693031 | 1 | 145441552 | 91.40 | 4.91E-10 | intron | SLC2A1-AS1 | TXNIP | trans |
| 4,660,240 | 1:43433286 | cg19693031 | 1 | 145441552 | 91.40 | 4.91E-10 | intron | SLC2A1-AS1 | TXNIP | trans |
| 12356274 | 10:115290365 | cg13547913 | 4 | 48831680 | -61.64 | 1.38E-10 | intergenic | none | OCIAD1 | trans |
| 2419834 | 10:115296495 | cg13547913 | 4 | 48831680 | -61.78 | 1.16E-10 | intergenic | none | OCIAD1 | trans |
| 11196365 | 10:115298288 | cg13547913 | 4 | 48831680 | -61.78 | 1.16E-10 | intergenic | none | OCIAD1 | trans |
| 7898594 | 10:115298906 | cg13547913 | 4 | 48831680 | -62.67 | 6.10E-11 | intergenic | none | OCIAD1 | trans |
| 55760941 | 10:115298957 | cg13547913 | 4 | 48831680 | -62.61 | 6.59E-11 | intergenic | none | OCIAD1 | trans |
| 1857320 | 10:115300285 | cg13547913 | 4 | 48831680 | -62.92 | 5.70E-11 | intergenic | none | OCIAD1 | trans |
| 1857319 | 10:115300382 | cg13547913 | 4 | 48831680 | -62.99 | 5.27E-11 | intergenic | none | OCIAD1 | trans |
| 11596601 | 10:115300407 | cg13547913 | 4 | 48831680 | -62.99 | 5.27E-11 | intergenic | none | OCIAD1 | trans |
| 10509979 | 10:115301699 | cg13547913 | 4 | 48831680 | -63.78 | 2.26E-11 | intergenic | none | OCIAD1 | trans |
| 4457677 | 10:115302658 | cg13547913 | 4 | 48831680 | -62.99 | 5.27E-11 | intergenic | none | OCIAD1 | trans |
| 57919847 | 10:115303435 | cg13547913 | 4 | 48831680 | -63.78 | 2.26E-11 | intergenic | none | OCIAD1 | trans |
| 1157916 | 10:115303743 | cg13547913 | 4 | 48831680 | -62.99 | 5.27E-11 | intergenic | none | OCIAD1 | trans |
| 4342960 | 10:115304399 | cg13547913 | 4 | 48831680 | -62.99 | 5.27E-11 | intergenic | none | OCIAD1 | trans |
| 11196368 | 10:115304614 | cg13547913 | 4 | 48831680 | -62.99 | 5.27E-11 | intergenic | none | OCIAD1 | trans |
| 118011654 | 10:115305727 | cg13547913 | 4 | 48831680 | -62.99 | 5.27E-11 | upstream-gene | none | OCIAD1 | trans |
| 4311988 | 10:115306261 | cg13547913 | 4 | 48831680 | -63.78 | 2.26E-11 | upstream-gene | none | OCIAD1 | trans |
| 10885471 | 10:115307040 | cg13547913 | 4 | 48831680 | -62.60 | 6.29E-11 | upstream-gene | none | OCIAD1 | trans |
| 76070905 | 10:115308927 | cg13547913 | 4 | 48831680 | -62.76 | 5.97E-11 | upstream-gene | none | OCIAD1 | trans |
| 59096313 | 17:1661829 | cg11692409 | 17 | 1665181 | -58.43 | 5.30E-10 | upstream-gene | none | SERPINF1 | cis |
| 62088168 | 17:1662296 | cg11692409 | 17 | 1665181 | 97.30 | 7.39E-21 | upstream-gene | none | SERPINF1 | cis |
| 7010095 | 8:98766461 | cg13547913 | 4 | 48831680 | 64.95 | 2.46E-10 | intergenic | none | OCIAD1 | trans |
| 2917964 | 8:98766490 | cg13547913 | 4 | 48831680 | 64.95 | 2.46E-10 | intergenic | none | OCIAD1 | trans |
| 7002076 | 8:98767981 | cg13547913 | 4 | 48831680 | 64.95 | 2.46E-10 | intergenic | none | OCIAD1 | trans |
| 112977944 | 8:98768643 | cg13547913 | 4 | 48831680 | 65.43 | 1.92E-10 | intergenic | none | OCIAD1 | trans |
| 12546567 | 8:98769090 | cg13547913 | 4 | 48831680 | 64.90 | 2.55E-10 | intergenic | none | OCIAD1 | trans |
| 148246392 | 8:98770499 | cg13547913 | 4 | 48831680 | 64.17 | 3.82E-10 | intergenic | none | OCIAD1 | trans |
| 185918087 | 8:98771524 | cg13547913 | 4 | 48831680 | 64.20 | 3.34E-10 | intergenic | none | OCIAD1 | trans |
a: chr and position of the CpG. *Beta column indicates the effect size from regression analysis