Table 3.

Overview of MSNs-based delivery systems to targeted elimination of bacterial biofilm

Strategies	Targeting ligands	Bacterial biofilm	Nancarriers	Refs.
Ligand-targeted	Lectin concanavalin A (ConA)	E. coli	MSNConA@LEVO	[155]
	Lysostaphin、serrapeptase、DNase I	Methicillin-resistant S. aureus (MRSA)	Lys/Ser/DN@MSN	[158]
Electrostatic interactions	Polyethyleneimine (PEI)	S. aureus	AHMSN@GA@PEI@Cur	[160]
	N-(2-aminoethyl)-3- aminopropyltrimethoxysilane (DAMO)	E. coli	MSN-DAMO@LEVO	[135]