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. 2023 Sep 8;2023(9):CD014805. doi: 10.1002/14651858.CD014805.pub2

Comparison 7. Type of platinum agent.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
7.1 Disease‐free survival 13 3347 Hazard Ratio (IV, Fixed, 95% CI) 0.65 [0.56, 0.74]
7.1.1 Carboplatin 12 3222 Hazard Ratio (IV, Fixed, 95% CI) 0.65 [0.57, 0.75]
7.1.2 Lobaplatin 1 125 Hazard Ratio (IV, Fixed, 95% CI) 0.21 [0.05, 0.98]
7.2 Overall survival 12   Hazard Ratio (IV, Fixed, 95% CI) Subtotals only
7.2.1 Carboplatin 12 3229 Hazard Ratio (IV, Fixed, 95% CI) 0.69 [0.58, 0.83]
7.3 Pathological complete response 16 3148 Risk Ratio (M‐H, Fixed, 95% CI) 1.46 [1.33, 1.61]
7.3.1 Carboplatin 13 2801 Risk Ratio (M‐H, Fixed, 95% CI) 1.45 [1.32, 1.60]
7.3.2 Cisplatin 2 222 Risk Ratio (M‐H, Fixed, 95% CI) 1.00 [0.58, 1.75]
7.3.3 Lobaplatin 1 125 Risk Ratio (M‐H, Fixed, 95% CI) 3.05 [1.48, 6.26]