Comparison 10. Schedule of platinum agent.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
10.1 Disease‐free survival	13	3347	Hazard Ratio (IV, Fixed, 95% CI)	0.65 [0.56, 0.74]
10.1.1 3‐weekly platinum	9	1906	Hazard Ratio (IV, Fixed, 95% CI)	0.71 [0.59, 0.85]
10.1.2 2‐weekly platinum	1	143	Hazard Ratio (IV, Fixed, 95% CI)	0.31 [0.14, 0.70]
10.1.3 Weekly platinum	3	1298	Hazard Ratio (IV, Fixed, 95% CI)	0.58 [0.45, 0.74]
10.2 Overall survival	12	3229	Hazard Ratio (IV, Fixed, 95% CI)	0.69 [0.58, 0.83]
10.2.1 3‐weekly platinum	8	1791	Hazard Ratio (IV, Fixed, 95% CI)	0.79 [0.64, 0.99]
10.2.2 2‐weekly platinum	1	143	Hazard Ratio (IV, Fixed, 95% CI)	0.14 [0.04, 0.52]
10.2.3 Weekly platinum	3	1295	Hazard Ratio (IV, Fixed, 95% CI)	0.55 [0.39, 0.78]
10.3 Pathological complete response	16	3148	Risk Ratio (M‐H, Fixed, 95% CI)	1.46 [1.33, 1.61]
10.3.1 3‐weekly platinum	11	1837	Risk Ratio (M‐H, Fixed, 95% CI)	1.61 [1.38, 1.87]
10.3.2 Weekly platinum	5	1311	Risk Ratio (M‐H, Fixed, 95% CI)	1.34 [1.19, 1.52]