2. Infectious events.
Intervention | Control | |||||||||||||
Study | N | Surgical site infection | Respiratory infection | UTI | Sepsis | Other infections | Total no. events | N | Surgical site infection | Respiratory infection | UTI | Sepsis | Other infections | Total no. events |
Cancer | ||||||||||||||
Galaal 2019 (TIC TOC) | 26 | 0 | 29 | 0 | ||||||||||
TOTAL | 26 | 0 | 29 | 0 | ||||||||||
Events PPR | 0 | 0 | ||||||||||||
CV (vascular) | ||||||||||||||
Clagett 1999 | 50 | 3 | 0 | 2 | 5 | 50 | 3 | 3 | 4 | 10 | ||||
Davies 1987 | 25 | 0 | 25 | 0 | ||||||||||
Mercer 2004 | 40 | 0 | 4 | 4 | 1 | 9 | 41 | 1 | 12 | 9 | 0 | 22 | ||
Spark 1997 | 23 | 0 | 0 | 27 | 3 | 3 | ||||||||
Thompson 1990 | 33 | 0 | 0 | 34 | 1 | 1 | ||||||||
TOTAL | 171 | 3 | 4 | 2 | 4 | 1 | 14 | 177 | 5 | 18 | 4 | 9 | 0 | 36 |
Events PPR | 0.082 | 0.203 | ||||||||||||
CV (no bypass) | ||||||||||||||
Damgaard 2006 | 30 | 0 | 2 | 2 | 29 | 2 | 3 | 5 | ||||||
Goel 2007 | 24 | 0 | 0 | 25 | 0 | 0 | ||||||||
Murphy 2005 | 30 | 2 | 2 | 31 | 1 | 1 | ||||||||
TOTAL | 84 | 0 | 2 | 2 | 4 | 85 | 2 | 3 | 1 | 6 | ||||
Events PPR | 0.048 | 0.071 | ||||||||||||
CV (with bypass) | ||||||||||||||
Eng 1990 | 20 | 0 | 0 | 20 | 1 | 1 | ||||||||
Klein 2008 | 102 | 6 | 2 | 8 | 111 | 5 | 1 | 6 | ||||||
Page 1989 | 48 | 0 | 0 | 51 | 0 | 0 | ||||||||
Parrot 1991 | 43 | 0 | 0 | 22 | 0 | 0 | ||||||||
Reyes 2011 | 34 | 5 | 5 | 29 | 4 | 4 | ||||||||
Schaff 1978 | 63 | 1 | 1 | 51 | 3 | 3 | ||||||||
Schmidt 1996 | 53 | 1 | 1 | 56 | 3 | 3 | ||||||||
Shen 2016 | 53 | 3 | 4 | 7 | 50 | 2 | 4 | 6 | ||||||
Thurer 1979 | 54 | 0 | 0 | 0 | 59 | 1 | 1 | 2 | ||||||
Vermeijden 2015 | 364 | 8 | 30 | 13 | 7 | 58 | 352 | 8 | 23 | 9 | 6 | 46 | ||
Ward 1993 | 18 | 1 | 1 | 17 | 0 | 0 | ||||||||
TOTAL | 852 | 20 | 30 | 13 | 0 | 18 | 81 | 818 | 23 | 23 | 10 | 0 | 15 | 71 |
Events PPR | 0.095 | 0.087 | ||||||||||||
Orthopaedic (hip) | ||||||||||||||
Cheung 2010 | 53 | 0 | 0 | 100 | 2 | 2 | ||||||||
Horstmann 2012 | 50 | 0 | 50 | 0 | ||||||||||
Horstmann 2013 | 102 | 2 | 2 | 102 | 0 | 0 | ||||||||
Horstmann 2014a | 56 | 1 | 1 | 62 | 0 | 0 | ||||||||
Kleinert 2012 | 40 | 0 | 0 | 0 | 0 | 0 | 0 | 80 | 0 | 0 | 0 | 0 | 0 | 0 |
Rollo 1995 | 75 | 0 | 1 | 1 | 40 | 0 | 0 | 0 | ||||||
Teetzman 2014 | 74 | 1 | 1 | 2 | 87 | 1 | 2 | 0 | 3 | |||||
Thomassen 2012 | 106 | 1 | 1 | 110 | 1 | 1 | ||||||||
TOTAL | 556 | 0 | 3 | 1 | 0 | 3 | 7 | 631 | 4 | 0 | 2 | 0 | 6 | |
Events PPR | 0.013 | 0.010 | ||||||||||||
Orthopaedic (knee) | ||||||||||||||
Amin 2008 | 92 | 3 | 2 | 5 | 86 | 2 | 2 | 4 | ||||||
Blatsoukas 2010 | 163 | 5 | 5 | 85 | 3 | 3 | ||||||||
Dutton 2012 | 23 | 0 | 0 | 25 | 1 | 1 | ||||||||
Horstmann 2014b | 59 | 1 | 1 | 56 | 0 | 0 | ||||||||
Munteanu 2009 | 50 | 3 | 3 | 50 | 3 | 3 | ||||||||
Newman 1997 | 35 | 1 | 1 | 35 | 3 | 3 | ||||||||
Šarkanoviü 2013 | 55 | 0 | 0 | 57 | 1 | 1 | ||||||||
Schnurr 2018 | 100 | 0 | 0 | 100 | 0 | 0 | ||||||||
Shenolikar 1997 | 50 | 1 | 1 | 2 | 50 | 1 | 1 | 2 | ||||||
Thomas 2001 | 115 | 0 | 116 | 0 | ||||||||||
TOTAL | 742 | 12 | 3 | 2 | 17 | 660 | 10 | 1 | 3 | 3 | 17 | |||
Events PPR | 0.023 | 0.026 | ||||||||||||
Orthopaedic (spinal) | ||||||||||||||
NCT 01251042 | 26 | 1 | 1 | 2 | 23 | 0 | 0 | 0 | ||||||
Nemani 2019 | 30 | 0 | 33 | 0 | 0 | |||||||||
TOTAL | 56 | 1 | 1 | 2 | 56 | 0 | 0 | 0 | ||||||
Events PPR | 0.036 | 0 | ||||||||||||
Orthopaedic (mixed) | ||||||||||||||
Gannon 1991 | 124 | 0 | 0 | 115 | 0 | 0 | ||||||||
Mac 1993 | 56 | 2 | 2 | 35 | 0 | 0 | ||||||||
Moonen 2007 | 80 | 0 | 80 | 0 | ||||||||||
Thomassen 2014 | 385 | 4 | 4 | 8 | 190 | 1 | 0 | 1 | ||||||
TOTAL | 645 | 6 | 4 | 0 | 10 | 420 | 1 | 0 | 0 | 1 | ||||
Events PPR | 0.016 | 0.002 | ||||||||||||
All surgeries | ||||||||||||||
TOTAL | 3132 | 42 | 46 | 16 | 4 | 27 | 135 | 2876 | 45 | 45 | 19 | 9 | 19 | 137 |
Events PPR | 0.043 | 0.048 |
CV: cardiovascular; N: number of people analysed (as reported by the study); PPR: per person randomised; UTI: urinary tract infection
"Other infections" includes studies that reported line infection, cellulitis, diverticulitis, and any other reported infection.
Infections are events as reported per study, and is not number of people who had an infection (one person could have multiple infectious events, all of which may have been counted individually).
Where studies clearly reported number of people who had an infection (and not number of infectious events), we have analysed the data formally, and presented them in the summary of findings tables.