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. 2023 Sep 8;2023(9):CD001888. doi: 10.1002/14651858.CD001888.pub5

2. Infectious events.

  Intervention Control
Study N Surgical site infection Respiratory infection UTI Sepsis Other infections Total no. events N Surgical site infection Respiratory infection UTI Sepsis Other infections Total no. events
Cancer
Galaal 2019 (TIC TOC) 26           0 29           0
TOTAL 26           0 29           0
Events PPR             0             0
CV (vascular)
Clagett 1999 50 3 0 2     5 50 3 3 4     10
Davies 1987 25           0 25           0
Mercer 2004 40 0 4   4 1 9 41 1 12   9 0 22
Spark 1997 23   0       0 27   3       3
Thompson 1990 33 0         0 34 1         1
TOTAL 171 3 4 2 4 1 14 177 5 18 4 9 0 36
Events PPR             0.082             0.203
CV (no bypass)
Damgaard 2006 30 0 2       2 29 2 3       5
Goel 2007 24 0         0 25 0         0
Murphy 2005 30         2 2 31         1 1
TOTAL 84 0 2     2 4 85 2 3     1 6
Events PPR             0.048             0.071
CV (with bypass)
Eng 1990 20 0         0 20 1         1
Klein 2008 102 6       2 8 111 5       1 6
Page 1989 48       0   0 51       0   0
Parrot 1991 43         0 0 22         0 0
Reyes 2011 34         5 5 29         4 4
Schaff 1978 63 1         1 51 3         3
Schmidt 1996 53 1         1 56 3         3
Shen 2016 53 3       4 7 50 2       4 6
Thurer 1979 54 0   0     0 59 1   1     2
Vermeijden 2015 364 8 30 13   7 58 352 8 23 9   6 46
Ward 1993 18 1         1 17 0         0
TOTAL 852 20 30 13 0 18 81 818 23 23 10 0 15 71
Events PPR             0.095             0.087
Orthopaedic (hip)
Cheung 2010 53 0         0 100 2         2
Horstmann 2012 50           0 50           0
Horstmann 2013 102   2       2 102   0       0
Horstmann 2014a 56   1       1 62   0       0
Kleinert 2012 40 0 0 0 0 0 0 80 0 0 0 0 0 0
Rollo 1995 75 0       1 1 40 0       0 0
Teetzman 2014 74     1   1 2 87 1   2   0 3
Thomassen 2012 106         1 1 110 1         1
TOTAL 556 0 3 1 0 3 7 631 4 0 2 0   6
Events PPR             0.013             0.010
Orthopaedic (knee)
Amin 2008 92 3       2 5 86 2       2 4
Blatsoukas 2010 163 5         5 85 3         3
Dutton 2012 23   0       0 25   1       1
Horstmann 2014b 59   1       1 56   0       0
Munteanu 2009 50 3         3 50 3         3
Newman 1997 35   1       1 35     3     3
Šarkanoviü 2013 55 0         0 57 1         1
Schnurr 2018 100         0 0 100         0 0
Shenolikar 1997 50 1 1       2 50 1       1 2
Thomas 2001 115           0 116           0
TOTAL 742 12 3     2 17 660 10 1 3   3 17
Events PPR             0.023             0.026
Orthopaedic (spinal)
NCT 01251042 26 1       1 2 23 0       0 0
Nemani 2019 30           0 33 0         0
TOTAL 56 1       1 2 56 0       0 0
Events PPR             0.036             0
Orthopaedic (mixed)
Gannon 1991 124       0   0 115       0   0
Mac 1993 56 2         2 35 0         0
Moonen 2007 80           0 80           0
Thomassen 2014 385 4 4       8 190 1 0       1
TOTAL 645 6 4   0   10 420 1 0   0   1
Events PPR             0.016             0.002
All surgeries
TOTAL 3132 42 46 16 4 27 135 2876 45 45 19 9 19 137
Events PPR             0.043             0.048

CV: cardiovascular; N: number of people analysed (as reported by the study); PPR: per person randomised; UTI: urinary tract infection

"Other infections" includes studies that reported line infection, cellulitis, diverticulitis, and any other reported infection.

Infections are events as reported per study, and is not number of people who had an infection (one person could have multiple infectious events, all of which may have been counted individually).

Where studies clearly reported number of people who had an infection (and not number of infectious events), we have analysed the data formally, and presented them in the summary of findings tables.