| 13.1 Transfusions |
14 |
1641 |
Risk Ratio (M‐H, Random, 95% CI) |
0.52 [0.38, 0.72] |
| 13.1.1 Restrictive (Hb ≦ 80 g/L) |
6 |
900 |
Risk Ratio (M‐H, Random, 95% CI) |
0.38 [0.28, 0.51] |
| 13.1.2 Liberal (Hb > 80 g/L) |
4 |
156 |
Risk Ratio (M‐H, Random, 95% CI) |
0.50 [0.28, 0.90] |
| 13.1.3 No threshold/protocol reported |
4 |
585 |
Risk Ratio (M‐H, Random, 95% CI) |
0.76 [0.37, 1.57] |
| 13.2 Volume of transfusion (units) (PPR) |
5 |
433 |
Mean Difference (IV, Random, 95% CI) |
‐0.61 [‐1.04, ‐0.19] |
| 13.2.1 Restrictive (Hb ≦ 80 g/L) |
2 |
304 |
Mean Difference (IV, Random, 95% CI) |
‐0.09 [‐0.20, 0.02] |
| 13.2.2 Liberal (Hb > 80 g/L) |
3 |
129 |
Mean Difference (IV, Random, 95% CI) |
‐1.29 [‐1.69, ‐0.90] |
| 13.3 Volume of transfusion (units) (PPT) |
4 |
63 |
Mean Difference (IV, Random, 95% CI) |
‐1.74 [‐2.92, ‐0.55] |
| 13.3.1 Restrictive (Hb ≦ 80 g/L) |
2 |
0 |
Mean Difference (IV, Random, 95% CI) |
Not estimable |
| 13.3.2 Liberal (Hb > 80 g/L) |
2 |
44 |
Mean Difference (IV, Random, 95% CI) |
‐1.74 [‐2.92, ‐0.55] |
| 13.4 Mortality |
4 |
651 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
0.46 [0.06, 3.33] |
| 13.4.1 Restrictive (Hb ≦ 80 g/L) |
1 |
118 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
8.22 [0.16, 416.61] |
| 13.4.2 Liberal (Hb > 80 g/L) |
1 |
216 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
0.14 [0.00, 7.08] |
| 13.4.3 No threshold/protocol reported |
2 |
317 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
0.19 [0.01, 3.20] |
| 13.5 Blood loss (mL) |
10 |
1085 |
Mean Difference (IV, Random, 95% CI) |
‐78.13 [‐162.74, 6.48] |
| 13.5.1 Restrictive (Hb ≦ 80 g/L) |
4 |
622 |
Mean Difference (IV, Random, 95% CI) |
‐115.60 [‐240.14, 8.95] |
| 13.5.2 Liberal (Hb > 80 g/L) |
5 |
372 |
Mean Difference (IV, Random, 95% CI) |
‐86.79 [‐354.95, 181.36] |
| 13.5.3 No threshold/protocol reported |
1 |
91 |
Mean Difference (IV, Random, 95% CI) |
3.00 [‐86.67, 92.67] |
| 13.6 Reoperation for bleeding |
1 |
|
Risk Difference (M‐H, Random, 95% CI) |
Totals not selected |
| 13.6.1 No threshold/protocol reported |
1 |
|
Risk Difference (M‐H, Random, 95% CI) |
Totals not selected |
| 13.7 Infection |
4 |
549 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
0.72 [0.17, 2.98] |
| 13.7.1 Restrictive (Hb ≦ 80 g/L) |
1 |
0 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
Not estimable |
| 13.7.2 No threshold/protocol reported |
3 |
429 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
0.72 [0.17, 2.98] |
| 13.8 Wound complication |
4 |
609 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
0.94 [0.36, 2.45] |
| 13.8.1 Restrictive (Hb ≦ 80 g/L) |
2 |
278 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
0.80 [0.22, 2.89] |
| 13.8.2 Liberal (Hb > 80 g/L) |
1 |
216 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
0.53 [0.05, 5.15] |
| 13.8.3 No threshold/protocol reported |
1 |
115 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
1.94 [0.30, 12.58] |
| 13.9 Prosthetic joint infection (PJI) |
5 |
806 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
0.31 [0.05, 1.78] |
| 13.9.1 Restrictive (Hb ≦ 80 g/L) |
2 |
322 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
0.37 [0.05, 2.68] |
| 13.9.2 Liberal (Hb > 80 g/L) |
1 |
216 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
0.14 [0.00, 7.08] |
| 13.9.3 No threshold/protocol reported |
2 |
0 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
Not estimable |
| 13.10 Thrombosis (VTE) |
2 |
196 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
1.45 [0.24, 8.72] |
| 13.10.1 Restrictive (Hb ≦ 80 g/L) |
1 |
0 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
Not estimable |
| 13.10.2 No threshold/protocol reported |
1 |
96 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
1.45 [0.24, 8.72] |
| 13.11 DVT |
3 |
343 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
1.05 [0.20, 5.60] |
| 13.11.1 Restrictive (Hb ≦ 80 g/L) |
2 |
304 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
0.14 [0.00, 6.82] |
| 13.11.2 Liberal (Hb > 80 g/L) |
1 |
39 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
1.66 [0.26, 10.58] |
| 13.12 PE |
2 |
316 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
0.14 [0.00, 7.08] |
| 13.12.1 Restrictive (Hb ≦ 80 g/L) |
1 |
0 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
Not estimable |
| 13.12.2 Liberal (Hb > 80 g/L) |
1 |
216 |
Peto Odds Ratio (Peto, Fixed, 95% CI) |
0.14 [0.00, 7.08] |
| 13.13 CVA (stroke) |
1 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Totals not selected |
| 13.13.1 Liberal (Hb > 80 g/L) |
1 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Totals not selected |
| 13.14 Hospital LOS (days) |
4 |
542 |
Mean Difference (IV, Random, 95% CI) |
0.07 [‐0.37, 0.52] |
| 13.14.1 Restrictive (Hb ≦ 80 g/L) |
4 |
542 |
Mean Difference (IV, Random, 95% CI) |
0.07 [‐0.37, 0.52] |
