ChiCTR‐IOR‐17010508.
Methods | Elderly individuals undergoing spinal surgery were randomly allocated to one of two groups. Randomisation was performed using a random number table. It is unclear how allocation concealment was performed and maintained. The blinding status of participants, personnel, and outcome assessors is not described. |
Participants | The study aimed to randomise 60 elderly individuals, between 60 and 80 years of age and of both sexes, undergoing spinal surgery, to one of two groups: Group 1 (Autotransfusion group): N = 30 Group 2 (Control group): N = 30 |
Interventions |
Group 1 (Autotransfusion group): underwent perioperative cell salvage using leucocyte depletion filter and autotransfusion Group 2 (Control group): received allogeneic blood transfusion |
Outcomes | Outcomes reported: oxygenation index (OI), respiratory index (RI), alveloar surface‐active substances related proteins‐A concentration (SP‐A) (primary outcome), serum malondialdehyde (MDA), superoxide dismutase (SOD), interleukin 6 (IL‐6), tumour necrosis factor (TNF)‐alpha concentration, blood transfusion reactions, postoperative respiratory complications within 72 hours |
Notes |
Transfusion protocol: a transfusion protocol is not described Prospective registration status: the study was reported to be prospectively registered on the Chinese Clinical Trials registry. Ethical approval: the study was approved by the Ethics Committee of Second Affiliated Hospital of Zhejiang Chinese Medical University (No. 20156) on 14 January 2015. Language: study information on the Chinese Clinical Trials registry in Chinese and English languages Reason for awaiting classification status: this study corresponds to a trial registration only and lacks sufficient information about intervention and comparator to assess for inclusion. |