Wiefferink 2007.
Methods | Randomised controlled trial was conducted to investigate the influence of processing both shed mediastinal blood and residual cardiopulmonary bypass (CPB) blood in participants undergoing isolated primary elective myocardial re‐vascularisation. Participants were randomly allocated to intervention or control using sealed, opaque, sequentially‐numbered envelopes. The sequence of allocations was obtained from a computer‐generated random number list. Clinicians in the ICU were blinded to the group. |
Participants | 30 participants undergoing isolated primary elective myocardial revascularisation were randomly allocated to one of two groups: Group B (Autotransfusion group): n = 15; M/F = 13/2; mean (SD) age = 62 (11.0) years Group A (Control group): n = 15; M/F = 11/4; mean (SD) age = 66 (8.0) years |
Interventions |
Group B: autotransfusion group had their mediastinal and residual CPB blood processed by a continuous autotransfusion system (C.A.T.S. Fresenius, HemoCare) before reinfusion using the quality wash protocol. Group A: control group did not receive autotransfusion. It is unclear whether control group had residual bypass blood processed or not prior to re‐transfusion. |
Outcomes | Outcomes reported: number of participants transfused allogeneic blood, plasma D‐dimer levels. |
Notes |
Transfusion protocol: study does not describe a transfusion protocol Prospective registration status: unclear whether the study was prospectively registered Ethical approval: study was approved by the local ethical and research council Language: study was published in English Reason for awaiting classification status: unclear whether the control group had residual CPB circuit blood processed prior to re‐transfusion |