Skip to main content
. 2023 Sep 8;2023(9):CD001888. doi: 10.1002/14651858.CD001888.pub5

Wiefferink 2007.

Methods Randomised controlled trial was conducted to investigate the influence of processing both shed mediastinal blood and residual cardiopulmonary bypass (CPB) blood in participants undergoing isolated primary elective myocardial re‐vascularisation. Participants were randomly allocated to intervention or control using sealed, opaque, sequentially‐numbered envelopes. The sequence of allocations was obtained from a computer‐generated random number list. Clinicians in the ICU were blinded to the group.
Participants 30 participants undergoing isolated primary elective myocardial revascularisation were randomly allocated to one of two groups:
Group B (Autotransfusion group): n = 15; M/F = 13/2; mean (SD) age = 62 (11.0) years
Group A (Control group): n = 15; M/F = 11/4; mean (SD) age = 66 (8.0) years
Interventions Group B: autotransfusion group had their mediastinal and residual CPB blood processed by a continuous autotransfusion system (C.A.T.S. Fresenius, HemoCare) before reinfusion using the quality wash protocol.
Group A: control group did not receive autotransfusion. It is unclear whether control group had residual bypass blood processed or not prior to re‐transfusion.
Outcomes Outcomes reported: number of participants transfused allogeneic blood, plasma D‐dimer levels.
Notes Transfusion protocol: study does not describe a transfusion protocol
Prospective registration status: unclear whether the study was prospectively registered
Ethical approval: study was approved by the local ethical and research council
Language: study was published in English
Reason for awaiting classification status: unclear whether the control group had residual CPB circuit blood processed prior to re‐transfusion