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. 2023 Aug 24;15(17):4249. doi: 10.3390/cancers15174249

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Proportion of positively stained cells in the total number of stromal cells for (a,b) KI-67: primaries and recurrences n = 12, before and after denosumab n = 23; (c,d) SATB2: primaries n = 11 and recurrences n = 10, before denosumab n = 22 and after denosumab n = 21 and (e,f) RUNX2: primaries n = 11 and recurrences n = 10, before denosumab n = 21 and after denosumab n = 19. (a,c,e) Comparison of primary and recurrence in the samples of GCTB without denosumab therapy. (b,d,f) Comparison before and after denosumab therapy in the samples of GCTBs treated with denosumab. Violin diagram is used to show the distribution of the data, the individual data points are each the sample of one patient, small dotted lines show median and quartiles.